ISDIN Isdinceutics A.G.E. Reverse Night is a nourishing night cream designed to support the skin’s natural repair process while you sleep. Formulated with melatonin to boost the skin’s antioxidant defenses, carnosine to help prevent collagen breakdown, and Helichrysum Italicum extract to promote skin comfort, it works overnight to restore vitality, reduce signs of aging, and improve skin elasticity.